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Abbreviations PREOG: Polyphenol rich extract of Ocimum gratissimum DAAM1: Disheveled-associated activator of morphogenesis 1 RSPH6A: Radial spoke head 6 homolog A PTMA: Prothymosin 3-HSD1: 3-Hydroxysteroid dehydrogenase type 1 17-HSD: 17-Hydroxysteroid dehydrogenase type 3 StAR: Steroidogenic acute regulatory protein PND: Postnatal day CdCL: Cadmium chloride GSI: Gonadosomatic index EPI: Epididymal index SOD: Superoxide dismutase GST: Glutathione S-transferase GPx: Glutathione peroxides MDA: Malondialdehyde H2O2: Hydrogen peroxide GSH: Glutathione q-RT-PCR: Quantitative real time polymerase chain reaction ROS: Reacting oxygen specie DNA: Deoxyribonucleic acid AR: Acrosome reaction OS: Oxidative stress FSH: Follicle stimulating hormone LH: Luteinizing hormone T: Testosterone GnRH: Gonadotropin realizing hormone References Sijo JP, Sandro CE, Ashok A

However, excessively concentrated solutions may cause irritation that paradoxically reduces absorption by triggering protective mucus secretion

The lyophilized form should be allowed to come to room temperature in its sealed vial before opening to prevent moisture condensation that can accelerate degradation

In preclinical studies, GHK-Cu showed activity at remarkably low doses, approximately 0.5 mcg/kg in rodent models