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Defining a cTI responder as someone with at least an 80 ms drop from baseline to week 24, the researchers found response rates of 0% in the placebo group, 85.7% with 1.2 mg of pemvidutide, 75.0% with 1.8 mg, and 100% with 2.4 mg
A vitamin B12 deficiency affects energy levels and immune health and may cause neurological problems like numbness and tingling in your hands and feet
Contact your GP if B12 is significantly elevated without obvious explanation, remains high on repeat testing, or if you experience unexplained symptoms such as weight loss, persistent fatigue, night sweats, unusual bruising, or signs of liver disease
Individual clearance varies based on body composition, kidney function, and liver function, but the Phase 2 trial established the mean half-life at approximately 6 days for the once-weekly subcutaneous dose range of 0.5mg to 12mg
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