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Additionally, Vitamin C plays a crucial role in maintaining glutathione in its active, reduced state, while adequate levels of B-vitamins (particularly unmethylated B12 and folate) are necessary to support the methylation cycle that drives natural glutathione production

All animals were housed at standard temperature (~22C) and humidity-controlled conditions under a 14L:10D photoperiod and provided ad libitum access to water and a low-fat-purified diet upon arrival (10% calories from fat D12450H Research Diets Inc)

Duloxetine inhibits effects of MDMA (ecstasy) in vitro and in humans in a randomized placebo-controlled laboratory study