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Cell 180 , 373386 (2020)
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Further evidence for this notion comes from observations that Prx5 downregulation correlates with downregulation of molecular chaperones, and upregulation of proteins associated with neuroinflammation (Knoops et al., 2016)
Furthermore, GSTP1-1 has also been shown to bind and inhibit tumor necrosis factor receptor-associated factor 2 (TRAF2), an upstream activator of JNK, thus blocking the MAPK/JNK signaling cascade at multiple levels 29
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