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45 , D945D954 (2017)
Garvey WT, Blher M, Osorto Contreras CK, et al
J Dairy Sci 71:27822789 Loiselle MC, Ster C, Talbot BG, Zhao X, Wagner GF, Boisclair YR, Lacasse P (2009) Impact of postpartum milking frequency on the immune system and the blood metabolite concentration of dairy cows
Dysregulation of the tyrosinase enzyme is the main cause of melanogenesis inhibition Hyperpigmentation is the darkening or increase in the natural color of the skin usually due to an increased deposition of melanin (hypermelanosis) Less frequently, it may be caused by the deposition in the dermis of endogenous or exogenous pigments, such as hemosiderin, iron, or heavy metals The excess of melanin in the basal and suprabasal layers of the skin is due to either an abnormally high number of melanocytes or a normal melanocyte population
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