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B12 is poorly absorbed in these conditions, like other nutrients, but its deficiency from poor absorption also contributes to further negative changes in intestinal health
oocyte maturation, ovarian steroidogenesis, ovulation, implantation, formation of blastocyst, luteolysis and luteal maintenance in pregnancy) [14, 15, 18, 19, 41]
It contains four proline residues (27% of sequence), which impart conformational rigidity that resists proteolytic attack
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