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Most compounding pharmacies and research suppliers recommend starting with 25-50mg daily and increasing to 50-100mg based on tolerance and perceived effects
First pass metabolism typically results in low bioavailability, resulting in adjusted dosages
NICE guidelines recommend hydroxocobalamin 1 mg intramuscularly three times weekly for 2 weeks (without neurological involvement) or on alternate days until no further improvement (with neurological symptoms)
FAQ What is the standard dosage for vitamin B12 injections in adults
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