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While hormonal imbalance - in particular, excess estrogen - seems established as a main cause, the exact factors that determine the appearance of uterine fibroids, or their propensity to produce more severe symptoms - or, on the other hand, to be completely asymptomatic - are still largely unknown and under debate

SpringerPlus 4 , 199 (2015)

TB-500, a synthetic analogue of thymosin beta-4, is a 43-amino acid peptide that was first characterized in the 1960s from bovine thymus tissue and has since been studied for its regenerative effects in wound healing and tissue remodeling

This is one of the few studies using human cells, but it is an in vitro model, not a clinical outcome