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This metabolic stability contrasts sharply with full-length growth hormone, which can cause glucose intolerance, elevated blood sugar, and insulin resistance (diabetogenic effects)

As a general rule, IM is favored when the goal is rapid correction of a clinical deficiency, when the patient has difficulty absorbing B12 through oral or sublingual routes, or when a provider wants predictable peak serum levels

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This makes it easier to ensure your B12 gets right into the muscle and not into the fat or lost somewhere in between