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Monitoring overlapping effects is particularly important when establishing a retatrutide dosage schedule after high dose of tirzepatide, especially since both peptides have extended half-lives
Brand-name GLP-1 medications like Wegovy or Zepbound are usually at the higher end, while compounded versions may cost less
Figure 1: Changes in body weight from baseline to the end of treatment at week 26 associated with the trial product estimand, in the randomly assigned treatment groups administered either 0.3 mg of cagrilintide, 0.6 mg of cagrilintide, 1.2 mg of cagrilintide, 2.5 mg of cagrilintide, 4.5 mg of cagrilintide, 3.0 mg of liraglutide, or a placebo
