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Previous studies have revealed that migraine patients suffer from impaired insulin sensitivity and have higher blood glucose levels [28]
Consequently, our data illuminate a novel role of IGF-1 in regulating stress-induced hepatocyte premature senescence in liver fibrosis: prolonged IGF-1 relieves oxidative stress-initiated hepatocyte premature senescence via inhibition of nuclear p53progerin interaction to ameliorate hepatic steatosis and fibrogenesis
Glucagon-like peptide-1 (GLP-1) receptor agonists are medications licensed in the UK for managing type 2 diabetes and, in some cases, obesity
doi:10.1016/S0736-0266(03)00110-4 Goldstein AL, Hannappel E, Sosne G, Kleinman HK
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