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In Amaranthus and blackgrass, targeting eccDNA maintenance through inhibition of replicon encoded replication or recombination factors, disruption of tethering motifs, or epigenetic re-silencing of TE-rich circles could reduce the rate at which resistant genotypes arise and are maintained under herbicide pressure
Interesting, and difficult to explain, that B12 is recommended without determining whether or not you are deficient in B12
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As mentioned, Vitamin C is a great partner
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