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Patients transitioning from insulin to GLP-1 therapy report better glucose control and weight loss, but this shift requires careful medical supervision

Although the pathogenesis is not completely clear, the role of mucosal epithelial cell apoptosis, oxidative damage, retention of decomposed products, changes to the mast cells and other factors has aroused attention

Current evidence from large clinical trials and observational studies does not establish a causal link between these diabetes and weight management medications and suicidal thoughts