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Death receptors (e.g., TNFR and Fas), Toll-like receptors, and cytosolic nucleic acid sensors form an autocrine feedback loop [98], recruiting proteins such as TRADD and the linear ubiquitin chain assembly complex, which further interact with caspase-8 and RIPK1 to promote RIPK1 ubiquitination
Lammi, Carmen, and Anna Arnoldi
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