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Although the time course of Nrf2 stabilization and nuclear translocation indicated a rapid increase with a peak at approximately 6 h for DEM, and a slow but gradual rise triggered by NFT, maximal accumulation of Nrf2 protein, as well as the induction of GCLC and glutathione synthesis, were almost identical for both NFT and DEM after incubation periods of and beyond 24 h (Fig

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MetaNeighbor analysis showed cells segregated into two principal clusters, corresponding to homeostatic microglia and DAMs/PVMs (Supplementary Fig

NF-kappaB activation by reactive oxygen species: fifteen years later